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The applicant followed the order of operations described in the following table and calculated a final inflated average case-weighted standardized charge per case of $230,414 which exceeded the average case-weighted threshold amount of $130,279

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The role of CHAC1 in apoptosis is highlighted by its function as a pro-apoptotic factor that can deplete intracellular GSH levels, reducing the cell’s ability to counteract ROS and oxidative stress, thereby promoting apoptotic cell death

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